WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Staphylococcus aureus infection       ID:05150
C=55; O=4; E=0.07; R=56.01; rawP=8.27e-07; adjP=1.08e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
2  ENSG00000171051 NA FPR1 formyl peptide receptor 1 2357 ENSG00000171051
3  ENSG00000171049 NA FPR2 formyl peptide receptor 2 2358 ENSG00000171049
4  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431


Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=5; E=0.34; R=14.53; rawP=2.49e-05; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
2  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
3  ENSG00000115607 NA IL18RAP interleukin 18 receptor accessory protein 8807 ENSG00000115607
4  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
5  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535


Database:KEGG pathway       Name:Osteoclast differentiation       ID:04380
C=128; O=3; E=0.17; R=18.05; rawP=0.0006; adjP=0.0026
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170866 NA LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 11026 ENSG00000170866
2  ENSG00000101307 NA SIRPB1 signal-regulatory protein beta 1 10326 ENSG00000101307
3  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747


Database:KEGG pathway       Name:Epithelial cell signaling in Helicobacter pylori infection       ID:05120
C=68; O=2; E=0.09; R=22.65; rawP=0.0036; adjP=0.0117
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871


Database:KEGG pathway       Name:Amoebiasis       ID:05146
C=106; O=2; E=0.14; R=14.53; rawP=0.0085; adjP=0.0221
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021355 NA SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1992 ENSG00000021355
2  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520


Database:KEGG pathway       Name:Phagosome       ID:04145
C=153; O=2; E=0.20; R=10.07; rawP=0.0170; adjP=0.0283
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
2  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431


Database:KEGG pathway       Name:Jak-STAT signaling pathway       ID:04630
C=155; O=2; E=0.20; R=9.94; rawP=0.0174; adjP=0.0283
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118971 NA CCND2 cyclin D2 894 ENSG00000118971
2  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535


Database:KEGG pathway       Name:Natural killer cell mediated cytotoxicity       ID:04650
C=136; O=2; E=0.18; R=11.33; rawP=0.0136; adjP=0.0283
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
2  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747


Database:KEGG pathway       Name:Chemokine signaling pathway       ID:04062
C=189; O=2; E=0.25; R=8.15; rawP=0.0252; adjP=0.0364
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871


Database:KEGG pathway       Name:Endocytosis       ID:04144
C=201; O=2; E=0.26; R=7.66; rawP=0.0282; adjP=0.0367
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).